Responding to the explosion in nucleotide chemistry research in both biotechnology and pharmaceutical industries, Current Protocols in Nucleic Acid Chemistry provides molecular biologists and organic chemists with an updatable publication of step-by-step laboratory procedures for the synthesis, modification, purification, analysis, and utilization of nucleic acids. Subscribers can find everything from the basic fundamentals of lab work to the most cutting-edge methods. All protocols have been contributed by leading investigators in their fields so subscribers can confidently move forward with their experimental procedures. Current Protocols in Nucleic Acid Chemistry is organized into subject area by chapter and then broken into units, each covering a different method. Overview units, presenting important theory and conceptual background, help the researcher select the most appropriate method.